Expert Consensus Statement for the Management of Patients With Embolic Stroke of Undetermined Source and Patent Foramen Ovale: A Clinical Guide by the Working Group for Stroke of the Hellenic Society of Cardiology and the Hellenic Stroke Organization

Δημοσίευση στις 2020 Mar 2 στο PubMed: https://pubmed.ncbi.nlm.nih.gov/32135273/?from_term=tsioufis&from_sort=date&from_size=200&from_pos=1

Georgios Ntaios

, Apostolos Tzikas

, Emmanouil Vavouranakis

, Dimitrios Nikas

, Georgios Katsimagklis

, Eleni Koroboki

, Antonis S Manolis

, Haralampos Milionis

, Konstantinos Papadopoulos

, Skevos Sideris
0
, Konstantinos Spengos

, Konstantinos Toutouzas

, Dimitrios Tziakas

, Sofia Vassilopoulou

, Ioannis Kanakakis

, Konstantinos Vemmos

, Konstantinos Tsioufis

2020 Mar 2[Online ahead of print]

Georgios Ntaios¹, Apostolos Tzikas², Emmanouil Vavouranakis³, Dimitrios Nikas⁴, Georgios Katsimagklis⁵, Eleni Koroboki⁶, Antonis S Manolis⁷, Haralampos Milionis⁸, Konstantinos Papadopoulos⁹, Skevos Sideris¹⁰, Konstantinos Spengos¹¹, Konstantinos Toutouzas¹², Dimitrios Tziakas¹³, Sofia Vassilopoulou¹⁴, Ioannis Kanakakis¹⁵, Konstantinos Vemmos¹⁶, Konstantinos Tsioufis¹⁷

Affiliations

¹ Department of Internal Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece. Electronic address: [email protected]
² AHEPA University Hospital & European Interbalkan Medical Center, Thessaloniki, Greece.
³ Third Department of Cardiology, National and Kapodistrian University of Athens, Greece.
⁴ 1(st) Cardiology Clinic, Ioannina University Hospital, Ioannina, Greece.
⁵ 1(st) Cardiology Department & Catheterization Laboratory, Naval Hospital of Athens, Athens, Greece.
⁶ Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Greece.
⁷ First and Third Department of Cardiology, Athens University School of Medicine, Athens, Greece.
⁸ Department of Internal Medicine, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
⁹ Echocardiography Laboratory, European Interbalkan Medical Center, Thessaloniki, Greece.
¹⁰ Department of Cardiology, Hippocratio Hospital, Athens, Greece.
¹¹ Department of Neurology, Hygeia Hospital, Athens, Greece.
¹² First Department of Cardiology, Hippocratio Hospital, Athens Medical School, Athens, Greece.
¹³ Cardiology Department & Cardiac Catheterization Lab, University Hospital of Alexandroupolis, Hellas.
¹⁴ First Department of Neurology, National and Kapodistrian University of Athens, Greece.
¹⁵ Catheterization Laboratory, Alexandra General Hospital, Athens, Greece.
¹⁶ Hellenic Stroke Organization.
¹⁷ 1st Department of Cardiology, National and Kapodistrian University of Athens, Greece.

Item in Clipboard

Georgios Ntaios et al.

Hellenic J Cardiol.

2020

Authors

Affiliations

¹ Department of Internal Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece. Electronic address: [email protected]
² AHEPA University Hospital & European Interbalkan Medical Center, Thessaloniki, Greece.
³ Third Department of Cardiology, National and Kapodistrian University of Athens, Greece.
⁴ 1(st) Cardiology Clinic, Ioannina University Hospital, Ioannina, Greece.
⁵ 1(st) Cardiology Department & Catheterization Laboratory, Naval Hospital of Athens, Athens, Greece.
⁶ Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Greece.
⁷ First and Third Department of Cardiology, Athens University School of Medicine, Athens, Greece.
⁸ Department of Internal Medicine, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
⁹ Echocardiography Laboratory, European Interbalkan Medical Center, Thessaloniki, Greece.
¹⁰ Department of Cardiology, Hippocratio Hospital, Athens, Greece.
¹¹ Department of Neurology, Hygeia Hospital, Athens, Greece.
¹² First Department of Cardiology, Hippocratio Hospital, Athens Medical School, Athens, Greece.
¹³ Cardiology Department & Cardiac Catheterization Lab, University Hospital of Alexandroupolis, Hellas.
¹⁴ First Department of Neurology, National and Kapodistrian University of Athens, Greece.
¹⁵ Catheterization Laboratory, Alexandra General Hospital, Athens, Greece.
¹⁶ Hellenic Stroke Organization.
¹⁷ 1st Department of Cardiology, National and Kapodistrian University of Athens, Greece.

Item in Clipboard

Abstract

Patent foramen ovale (PFO) is a frequent echocardiographic finding and can be found in approximately 15-25% of the general population1 (Figure 1). The incidence of PFO is 2- to 3-fold higher in patients with stroke of undetermined etiology compared to the general population, a finding that implies a causative role of PFO in patients with stroke of undetermined etiology ²^,³. In this context, percutaneous PFO closure has been increasingly used as a strategy to prevent stroke recurrence in patients with stroke of no apparent cause ⁴. During the recent years, evidence about the efficacy and safety of this strategy has accumulated through observational studies and well-designed randomized trials^5-12.This paper is a consensus statement of expert panelists from the Hellenic Stroke Organization (HSO) and the Working Group for Stroke of the Hellenic Society of Cardiology (HSC) for the secondary prevention in patients with embolic stroke of undetermined source and PFO. It aims to assist clinicians, patients/families and the Hellenic regulatory authorities to design optimal secondary prevention strategies for this patient population. The recommendations of the panelists are summarized in Table 1.

Keywords:

PFO closure; Patent foramen ovale; embolic stroke of undetermined source.

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Κωνσταντίνος Τσιούφης

Ο Κωνσταντίνος Τσιούφης είναι Καθηγητής Καρδιολογίας στο Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών. Απόφοιτος του ’87 με βαθμό “ΑΡΙΣΤΑ”, εργάζεται στο Ιπποκράτειο Γενικό Νοσοκομείο Αθηνών με τα κύρια αντικείμενα ενασχόλησής του να είναι η υπέρταση και η επεμβατική καρδιολογία.

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