Primary aldosteronism: novel insights.

By 17 Απριλίου 2019 29 Μαΐου, 2019 Δημοσιεύσεις

Δημοσίευση στις 2019/4/17 στο PubMed:


Stavropoulos K, Imprialos K, Papademetriou V, Faselis C, Tsioufis K, Dimitriadis K, Doumas M.



Primary aldosteronism is one of the most common causes of secondary hypertension. Patients with this endocrine syndrome are at increased cardiovascular risk, higher than hypertensive individuals with equal blood pressure levels.


To thoroughly present and critically discuss the novel insights in the field of primary aldosteronism, focusing in the clinically meaningful aspects.


We meticulously evaluated existing data in the field of primary aldosteronism in order to summarize future perspectives in this narrative review.


Novel data suggests that a subclinical form of primary aldosteronism might exist. Interesting findings might simplify the diagnostic procedure of the disease, especially for the localization of primary aldosteronism. The most promising progress has been noted in the field of molecular basis of the disease, suggesting new potential therapeutic targets.


Several significant aspects are at early stages of evaluation. Future research is essential to investigate these well-promising perspectives.